Role of surgery in the treatment of motor complications
Identifieur interne : 001427 ( Main/Exploration ); précédent : 001426; suivant : 001428Role of surgery in the treatment of motor complications
Auteurs : Leo Verhagen Metman [États-Unis] ; Shaun T. O'Leary [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2005-05.
English descriptors
Abstract
When medications no longer provide patients with Parkinson's disease a reasonable quality of life due to the presence of levodopa‐associated motor fluctuations and dyskinesias, surgical treatment is often pursued. Numerous studies have examined the antiparkinsonian efficacy of procedures currently available, but surprisingly few studies have evaluated their effect on motor response complications in a systematic, controlled manner, using appropriate instruments. Nonetheless, the combined evidence from uncontrolled case series and more recent randomized controlled trials reviewed here indicates that unilateral pallidotomy, bilateral pallidal deep brain stimulation, and bilateral subthalamic deep brain stimulation all substantially alleviate levodopa‐induced dyskinesias and, to a lesser extent, motor fluctuations. Incorporation of standardized, validated instruments for the quantification of motor response complications in future surgical study protocols will not only allow more accurate comparison of different interventions but also will help physicians select the most appropriate procedure for their patients. © 2005 Movement Disorder Society
Url:
DOI: 10.1002/mds.20480
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Role of surgery in the treatment of motor complications</title><author><name sortKey="Metman, Leo Verhagen" sort="Metman, Leo Verhagen" uniqKey="Metman L" first="Leo Verhagen" last="Metman">Leo Verhagen Metman</name></author><author><name sortKey="O Leary, Shaun T" sort="O Leary, Shaun T" uniqKey="O Leary S" first="Shaun T." last="O'Leary">Shaun T. O'Leary</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:65B4121D13BE10D465605D777AE82B47F1CC5375</idno><date when="2005" year="2005">2005</date><idno type="doi">10.1002/mds.20480</idno><idno type="url">https://api.istex.fr/document/65B4121D13BE10D465605D777AE82B47F1CC5375/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">000E11</idno><idno type="wicri:Area/Main/Curation">000C44</idno><idno type="wicri:Area/Main/Exploration">001427</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Role of surgery in the treatment of motor complications</title><author><name sortKey="Metman, Leo Verhagen" sort="Metman, Leo Verhagen" uniqKey="Metman L" first="Leo Verhagen" last="Metman">Leo Verhagen Metman</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="O Leary, Shaun T" sort="O Leary, Shaun T" uniqKey="O Leary S" first="Shaun T." last="O'Leary">Shaun T. O'Leary</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2005-05">2005-05</date><biblScope unit="volume">20</biblScope><biblScope unit="issue">S11</biblScope><biblScope unit="supplement">11</biblScope><biblScope unit="page" from="S45">S45</biblScope><biblScope unit="page" to="S56">S56</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">65B4121D13BE10D465605D777AE82B47F1CC5375</idno><idno type="DOI">10.1002/mds.20480</idno><idno type="ArticleID">MDS20480</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>DBS</term><term>Parkinson's disease</term><term>dyskinesias</term><term>motor complications</term><term>surgical intervention</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">When medications no longer provide patients with Parkinson's disease a reasonable quality of life due to the presence of levodopa‐associated motor fluctuations and dyskinesias, surgical treatment is often pursued. Numerous studies have examined the antiparkinsonian efficacy of procedures currently available, but surprisingly few studies have evaluated their effect on motor response complications in a systematic, controlled manner, using appropriate instruments. Nonetheless, the combined evidence from uncontrolled case series and more recent randomized controlled trials reviewed here indicates that unilateral pallidotomy, bilateral pallidal deep brain stimulation, and bilateral subthalamic deep brain stimulation all substantially alleviate levodopa‐induced dyskinesias and, to a lesser extent, motor fluctuations. Incorporation of standardized, validated instruments for the quantification of motor response complications in future surgical study protocols will not only allow more accurate comparison of different interventions but also will help physicians select the most appropriate procedure for their patients. © 2005 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Illinois</li></region></list><tree><country name="États-Unis"><region name="Illinois"><name sortKey="Metman, Leo Verhagen" sort="Metman, Leo Verhagen" uniqKey="Metman L" first="Leo Verhagen" last="Metman">Leo Verhagen Metman</name></region><name sortKey="O Leary, Shaun T" sort="O Leary, Shaun T" uniqKey="O Leary S" first="Shaun T." last="O'Leary">Shaun T. O'Leary</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001427 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001427 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:65B4121D13BE10D465605D777AE82B47F1CC5375
|texte= Role of surgery in the treatment of motor complications
}}
| This area was generated with Dilib version V0.6.23. |  |